An analysis of the effect of syringe barrel volume on mechanical failure during injection

Resumen

Background: syringes are critical medical devices whose mechanical integrity is essential to ensure safety during injections. The cylinder volume can influence their mechanical performance.
Objective: this study investigates how cylinder volume affects the mechanical integrity of syringes by analyzing von Mises stress, buckling risk, and overall safety during injection. 
Methods: autodesk Inventor 2021 and Ansys 2019 R2 were used to analyze syringes with volumes of 1 ml, 3 ml, 5 ml, and 10 ml. Von Mises stress and buckling susceptibility were evaluated during simulated injections.
Results: smaller syringes showed higher stress levels: 14.030 MPa for the 1 ml syringe, 10.532 MPa for the 3 ml, and 7.0150 MPa for the 5 ml and 10 ml. The 5 ml syringe was the most susceptible to buckling, with a critical pressure of -0.1757 MPa. Despite this, all designs are safe under normal operating conditions.
Conclusions: cylinder volume affects mechanical performance, but with proper design, even smaller syringes can remain safe, enhancing the reliability of medical treatments.